Hover over pathway elements to see detailed information
| Study Type | Population | EGCG Dose | Outcomes |
|---|---|---|---|
| In vitro | Synovial fibroblasts | 10-100 μM | ↓ TNF-α, IL-6, MMPs; ↓ NF-κB activation |
| Animal (CIA) | Mice | 10-50 mg/kg | ↓ Arthritis score, ↓ joint destruction |
| Human observational | >50,000 women | ≥3 cups tea/day | 21% lower RA risk |
| Human clinical | RA patients | 400-800 mg/day | ↓ CRP, ↓ DAS28 score |
2-4 cups daily (provides 50-100mg EGCG per cup)
200-400mg EGCG daily (follow product guidelines)
1-2 tsp daily in beverages or smoothies
Note: EGCG absorption is improved when taken with vitamin C and on an empty stomach.
Do not exceed 800mg EGCG/day from supplements without medical supervision
Avoid taking with iron-rich foods as it may inhibit iron absorption
Consult doctor if taking anticoagulants, statins, or methotrexate
Tip: Start with lower doses and gradually increase to assess tolerance.
EGCG simultaneously addresses inflammation, immune dysregulation, and tissue damage in RA through multiple pathways.
Clinical evidence shows EGCG can help preserve joint structure and function in RA patients.
EGCG works best alongside conventional RA treatments, not as a replacement.
Green tea provides EGCG with additional health benefits and few side effects when used appropriately.
Consult with your rheumatologist about incorporating green tea or EGCG supplements into your RA management plan.
This website uses cookies.